SANTA SANGRE is a horror drama about a young man who witnesses his mother being mutilated by his father. He then accompanies his mother as she takes her revenge upon those she believes have wronged her.

Violence

A woman takes revenge on her husband by throwing a jar of acid onto his genitals. The man then chops his wife's arms off with knives.A man slits his own throat, and there are several bloody stabbings.

There are several scenes in which knives are fetishised and/or sexualised. In two scenes a woman stands against a board while a man throws and stabs knives towards her. He encourages the woman to lick one of the knives in a sexual fashion and then rams another one into the board just below her crotch, causing her to whimper in mock sexual pleasure.

In another scene, a man imagines he is in a graveyard as dozens of naked women wearing bridal veils rise up from their graves and swarm all over him. The scene contains full frontal female nudity.